Want to know where the field of foldamers is going? Check this feature article in Chemistry World!
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As the shape determines the function, chemists have designed and synthesized aliphatic and aromatic foldamers able to mimic protein-protein interactions, catalyze chemical reactions or encapsulate guest molecules in their cavity. Because of the diversity of sizes, shapes and arrangements available with non-natural building blocks, foldamers are versatile frameworks to access structural motifs and functions beyond those of peptides and nucleotides.